Thymus vulgaris L. (T. vulgaris) a significant aromatic plant with around 100 species in the world is widely used for medicinal purposes as well as in culinary dishes. The genus Thymus are important medicinal plants, highly recommended due to a variety of therapeutic properties of their essential oils, normally known as Thyme oil. Thymus species are considered as medicinal plants due to their pharmacological and biological properties. Its properties are due to its main components, thymol and carvacrol. Fresh Thyme has the highest level of antioxidants among all herbs. Thymus vulgaris L. is widely used in folk medicine in the treatments of variety of diseases such as gastroenteric and bronchopulmonary disorders. The essential oil of thyme and the compound thymol have antimicrobial activity in vitro against E. coli strains. The essential oil of thyme has been found to possess the strongest antimicrobial properties. Thus the highlight of this paper was to review the medicinal and functional values of Thyme (Thymus vulgaris L.) herb.
Dauqan EMA, Abdullah A. Medicinal and Functional Values of Thyme (Thymus vulgaris L.) Herb. J App Biol Biotech. 2017; 5 (02): 017-022. DOI: 10.7324/JABB.2017.50203
1. Nanasombat S, Thonglong J, Jitlakha J. Formulation and characterization of novel functional beverages with antioxidant and anti-acetylcholinesterase activities. Functional Foods in Health and Disease. 2015; 5(1): 1-16.
2. Grigore A, Paraschiv INA, Colceru-mihul S, Bubueanu C, Draghici E, Ichim M. Chemical composition and antioxidant activity of Thymus vulgaris L. volatile oil obtained by two different methods. Romanian Biotechnological Letters, University of Bucharest. 2010; 15(4): 5436- 5443.
3. Mohamed A, Mohamed A, Omar AA. A study to find thyme oil dose that kill 50% of mice and minimal dose that kill all mice and maximum nonlethal Dose. Nature and Science. 2013; 11(12): 52-53.
4. Sharangi AB, Guha S. Wonders of leafy spices: Medicinal properties ensuring Human Health. Science International. 2013; 312-317, DOI: 10.17311/ sciintl.2013.312.317.
5. Alireza K, Faeghe H, Siamak S, Negar B. Study of the effect of extract of Thymus vulgaris on anxiety in male rats. Journal of Traditional and Complementary Medicine. 2015; 1-5.
6. Aksel B. Bioactive compounds in plants – benefits and risks for man and animals. The Norwegian Academy of Science and Letters, Oslo. 13 – 14 November 2008.
7. Ocana A, Reglero G. Effects of Thyme extract oils (from Thymus vulgaris, Thymuszygis, and Thymus hyemalis) on cytokine production and gene expression of oxLDL-Stimulated THP-1-Macrophages. Journal of Obesity. 2012; 1-11, Doi:10.1155/2012/104706.
8. Margaret E. Recognition for plant heritage thyme collection. Brickell Award for National Plant Collection Holder, Plant Heritage. 2011.
9. Hoopa Tribal Radio, KIDE. Health aatters, Thyme. The First Solar Powered Radio Station in California. 2014; 1-3.
10. Saleh H, Azizollah JK, Ahmadreza H, Raham A. The Application of Thymus vulgaris in traditional and modern medicine: A Review. Global Journal of Pharmacology. 2015; 9 (3): 260-266.
11. Echappees sauvages. Thym - Thymus vulgaris L. 2011.
12. Prasanth R, Ravi VK, Varsha PV, Satyam S. Review on Thymus vulgaris traditional uses and pharmacological properties. Med Aromat Plants. 2014; 3 (4):1-3.
13. Nadiya RM, Yadav KC, Anurag V. Optimization of process parameters in extraction of Thyme oil using response surface methodology (RSM). International Journal of Science, Engineering and Technology. 2016; 4(1): 248-256.
14. Directorate Agricultural Information Services. Department of Agriculture, Forestry and Fisheries Private Bag X144, Pretoria, 0001 South Africa. 2009.
15. Fatimah AA. Chemical composition, antioxidant and antitumor activity of Thymus vulgaris L. essential oil. Middle-East Journal of Scientific Research. 2014; 21 (10): 1670-1676.
16. Committee on Herbal Medicinal Products. Assessment report on Thymus vulgaris L., vulgaris zygis L., herba. European Medicines Agency. 2013.
17. Taheri M, Maleknia L, Alizadeh GhN, Almasian A, Chizarif AGh. Effect of zirconium dioxide nanoparticlesas A mordant on properties of wool with Thyme: Dyeing, flammability and antibacterial. An International Open Free Access, Peer Reviewed Research Journal. 2014; 31(1):85-96.
18. Hina J, Shazia E, Sobia T, Farhana A. An overview on medicinal importance of thymus vulgaris. Journal of Asian Scientific Research. 2013; 3(10):974-982
19. Vineetha. 22 Amazing benefits and uses of Thyme. Health Beckon. 2014. http://www.healthbeckon.com/thyme-benefits/
20. National Institutes of Health. 2016. Vitamin B6. U.S. Department of Health & Human Services. https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/
21. Moghtader M. Antifungal effects of the essential oil from Thymus vulgaris L. and comparison with synthetic thymol on Aspergillus niger. Journal of Yeast and Fungal Research. 2012; 3(6): 83 – 88.
22. AgroWeb. Thyme - The timeless herb of albania. 2016. http://agroweb.org/article.html?id=10&l=1229&ln=en&url=thyme-the-timeless-herb-of-albania
23. Eqbal D, Aminah A, Halimah AS. Review Article: Natural antioxidants, lipid profile, and antioxidant enzyme of vegetable oils. Advance Journal of food science and technology. 2011; 3(4): 308-316.
24. Dipak P. Role of antioxidants in stability of edible oil. Journal homepage. 2013; 1(1 ): 68-73
25. Eqbal D, Halimah AS, Aminah A. Antioxidants enzyme: Effect of different concentrations of red palm olein and different vegetable oils on antioxidant enzymes on normal and stressed. INTECH. 2012; ISBN 980-953-307-108-9. Pages: 303-320.
26. El-Nekeety AA, Mohamed SR, Hathout AS, Hassan NS, Aly SE, Wahhab MA. Antioxidant properties of Thymus vulgaris oil against aflatoxin-induce oxidative stress in male rats. Toxicon. 2011; 57: 984-991.
27. Natalie B. 9 Health benefits of Thyme. Healthline - Food & Nutrition. 2016. http://www.healthline.com/health/health-benefits-of-thyme#1
28. Hashim S, Gamil M. Plants and herbs between the Iraqi folk medicine and scientific research. Baghdad, Dar revolution of Press and Publication. 1988.
29. Mohsin A, Shah AH, Al-Yahya MA, Tariq M, Tanira MOM, Ageel AM. Analgesic, antipyretic activity and phytochemical screening of some plants used in traditional arab system of medicine. Fitoterapia. 1989; 60(2): 174-177.
30. Monira A, Naima. Z. Evaluation of protective and antioxidant activity of thyme (Thymus vulgaris) extract on paracetamol-induced toxicity in rats. Australian Journal of Basic and Applied Sciences. 2012; 6(7): 467-474.
31. Namsa ND, Tag H, Mandal M, Kalita P, Das AK. An ethnobotanical study of traditional anti-inflammatory plants used by the Lohit community of Arunachal Pradesh. India J Ethnopharmacol. 2009; 125(2): 234-45.
32. Verpoorte R. Pharmacognosy in the new millennium: leadfinding and biotechnology. J. Pharm Pharmacol. 2000; 52: 253-262.
33. Marina S, Jasmina G, Petar DM, Dejan B, Leo JLD. Antibacterial effects of the essential oils of commonly consumed medicinal herbs using an in vitro model. Molecules. 2010; 15: 7532-7546. DOI: 10.3390/molecules15117532.
34. Hompson J, Chalcha J., Michet A, Linhart Y, Ehlers B. Qualitative and quantitative variation in monoterpene co-occurrence and composition in the essential oil of Thymus vulgaris chemotypes., J. Chem Ecol. 2003; 29(4): 859-80.
35. ESCOP Monographs: The scientific foundation for herbal medicinal products. The European Scientific Cooperative on Phytotherapy in collaboration with Georg Thieme. 2007.
36. Marino M, Bersani CC. Antimicrobial Activity of the Essential Oils of Thymus vulgaris L. Measured Using a Bioimpedometri Method. J Food Prot. 1999; 62: 1017-23.
37. Boruga O, Jianu C, MiÅŸcÄƒ C, GoleÅ£ I, Gruia AT, Horhat FG. Thymus vulgaris essential oil: chemical composition and antimicrobial activity. Journal of Medicine and Life. 2014; 7( 3): 56-60
38. Gill AO, Delaquis P, Russo P, Holley RA. Evaluation of antilisterial action of cilantro oil on vacuum packed ham. International Journal of Food Microbiology. 2002; 73(1): 83-92.
39. Rota MC, Herrera A, Martínez RM, Sotomayor JA, Jordán MJ. Antimicrobial activity and chemical composition of Thymus vulgaris, Thymus zygis and Thymus hyemalis essential oils. Food Control. 2008; 19(7): 681-687.
40. Dorman HJD, Deans SG. Antimicrobial agents from plants: antibacterial activity of plant volatile oils. Journal of Applied Microbiology. 2000; 88(2): 308-316.
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